Sphere of influence may refer to:

• Sphere of influence (astrodynamics), the area, typically spherical, around a celestial body, e.g. a star, in which that body is the biggest gravitational influence
• Sphere of influence (black hole), a region around a black hole in which the gravitation of the black hole dominates that of the host bulge
• Sphere of influence, an area or region over which a state or organization has significant cultural, economic, military or political influence
• Sphere of influence is also a legal term in family law. A child can only be emancipated in some states when he or she goes outside of the sphere of influence of the parents, e.g. no longer needs their financial support.
• Nobunaga's Ambition: Sphere of Influence, a 2013 Japanese turn-based strategy video game

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