Sulfate_adenylyltransferase_(ADP)

Sulfate adenylyltransferase (ADP)

Sulfate adenylyltransferase (ADP)

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In enzymology, a sulfate adenylyltransferase (ADP) (EC 2.7.7.5) is an enzyme that catalyzes the chemical reaction

ADP + sulfate phosphate + adenylyl sulfate
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Thus, the two substrates of this enzyme are ADP and sulfate, whereas its two products are phosphate and adenylyl sulfate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is ADP:sulfate adenylyltransferase. Other names in common use include ADP-sulfurylase, sulfate (adenosine diphosphate) adenylyltransferase, and adenosine diphosphate sulfurylase. This enzyme participates in sulfur metabolism.

References

    • Grunberg-Manago M, Del Campillo-Campbell A, Dondon L, Michelson AM (1966). "[Yeast ADP-sulfurylase catalyzing an exchange between orthophosphate and the terminal phosphate of nucleoside diphosphates]". Biochim. Biophys. Acta. 123 (1): 1–16. doi:10.1016/0005-2787(66)90153-5. PMID 5964041.
    • ROBBINS PW, LIPMANN F (1957). "Isolation and identification of active sulfate". J. Biol. Chem. 229 (2): 837–51. PMID 13502346.


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