The Synod of Rome may refer to a number of synods or councils of the Roman Catholic Church, held in Rome.

Some of these synods include:

• Synod of Rome (313), attended by the bishop of Beneventum, and Reticius, bishop of Autun
• Council of Rome (382), a meeting of Christian Church officials and theologians under the authority of Pope Damasus I
• Synod of Rome (465), attended by Concordius, bishop of Bari
• Synod of Rome (499), attended by Saint Justus, bishop of Acerenza and Menecrates, bishop of Cariati
• Synod of Rome (721), a synod held in St. Peter's Basilica under the authority of Pope Gregory II
• Synods of Rome (727), held under the authority of Pope Gregory II
• Synods of Rome (731), two synods held in St. Peter's Basilica under the authority of Pope Gregory III
• Synod of Rome (732), a synod held in Rome under the authority of Pope Gregory III
• Synod of Rome (745) held under the authority of Pope Zachary
• Synod of Rome (898) Multiple councils held by John the XI to rectify the wrongs of the Cadaver Synod
• Synod of Rome (963), a possibly uncanonical synod held in St. Peter's Basilica under the authority of the Holy Roman Emperor to depose Pope John XII
• Synod of Rome (964), a synod held in St. Peter's Basilica, for the purpose of condemning the Synod of Rome (963) and to depose Pope Leo VIII

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