Thomas Gisborne (1789 – 20 July 1852) was an English Whig politician who sat in the House of Commons variously between 1830 and 1852.^[1]

Gisborne was the son of Thomas Gisborne, Prebendary of Durham. He was educated at Trinity College, Cambridge being awarded B.A. in 1810.^[2] He found success as a coal, lime, and sand merchant in Manchester, though he lived most of his life at his two estates: Horwick House, Derbyshire and Yoxall Lodge, Staffordshire.^[2]

He married Elizabeth Fysche Palmer, daughter of John Palmer of Ickwell in Bedfordshire, in 1811, and they had two sons before she died in 1823.^[1] Via his wife's sister, Susan, he was brother-in-law of Francis Dukinfield Astley, and there was a considerable scandal when Astley died suddenly at Horwick House in 1825 and Gisborne was accused of having poisoned him; however, he managed to clear his name after a coroner's inquest.^[3] Gisborne married the widowed Susan Astley in 1826.^[1]

At the 1830 UK general election Gisborne was elected Member of Parliament for Stafford and held the seat until 1832.^[4] In the reformed parliament after the 1832 UK general election he was elected MP for North Derbyshire and held the seat until 1837.^[5] On 27 Feb. 1839 he was elected MP for Carlow until 1841.^[1][6] He failed to win a seat in Ipswich in a by-election in 1842. He was elected MP for Nottingham in 1843 and held the seat until his defeat in 1847.^[7]

Gisborne died in 1852, at the age of 62.^[2] He was survived by his eldest son Thomas Guy Gisborne (1812–69).^[1] His second son—Henry Fyshe Gisborne (1813–41), a colonial commissioner—predeceased him.^[2]