Thomas James Smith (1827−1896) was the founder of Smith & Nephew, one of the United Kingdom's largest medical devices businesses.

After training as a pharmacist at a dispensing chemist in Grantham and then at University College, London, Thomas Smith opened his own chemist's shop in Hull in 1856.^[1] In 1858 he started selling cod-liver oil most of which came from Newfoundland although he obtained one large batch at a cheaper price from Norway: he sold these supplies to hospitals on a wholesale basis.^[1]

In 1896 he was joined by his nephew, Horatio Nelson Smith, who helped build T.J. Smith & Nephew into a global medical supplies business.^[1] Thomas Smith died later in 1896.^[1]

Smith, who never married, had no children.

He became President of the Hull Chamber of Commerce.^[2]