Thomas Wise or Tom Wise may refer to:

• Sir Thomas Wise (died 1630) (died 1629), English politician, MP for Bere Alston, 1621
• Thomas James Wise (1859–1937), manuscript forger
• Thomas Wise (died 1641) (c. 1605–1641), English politician
• Thomas Wise (priest) (1671–1726), clergyman of the Church of England
• Thomas A. Wise (1865–1928), American actor and president of The Lambs
• Thomas Dewey Wise (born 1939), American politician in the state of South Carolina
• Thomas Alexander Wise (1802–1889), Scottish physician, medical author, polymath and collector
• Tom Wise (politician) (born 1948), Independent and UKIP member of the European Parliament

• Thomas Wyse (1791–1862), Irish politician

This disambiguation page lists articles about people with the same name.
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