Tighe (/taɪ/) is an Irish surname, derived from the Old Gaelic Mac Tighe, which originated in Galway, or O Taidhg.^[1] Notable persons with that name include:

• Ambrose Tighe (1859–1928), American lawyer, politician, and academic
• Andrew Tighe (born 1955), Australian actor
• Brad Tighe (born 1984), Australian rugby league player
• Charles Tighe, (1927–2004), American lawyer and politician
• Dennis Tighe, (born 1960), American scientist, physician, and scholar
• Eugene F. Tighe (1921–1994), American military officer
• Jack Tighe (1913–2002), American baseball manager
• James Tighe (born 1982), British wrestler
• Jan E. Tighe (born 1962), American military officer
• Karen Tighe, Australian sports presenter
• Kevin Tighe (born 1944), American actor
• Mary Tighe (1772–1810), Irish poet
• Paul Tighe (born 1958), Irish Roman Catholic bishop
• Richard Lodge Tighe (1902-1938), American politician
• Robert Tighe (died 1620), English cleric and linguist
• Tommy Tighe, American sports radio broadcaster