Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complexes whose canonical function is to prevent leakage of solutes and water and seals between the epithelial cells. Tight junctions may also serve as leaky pathways by forming selective channels for small cations, anions, or water. Tight junctions are present mostly in vertebrates (with the exception of Tunicates[1]). The corresponding junctions that occur in invertebrates are septate junctions.

Tight junction
Diagram of Tight junction
Details
Identifiers
Latinjunctio occludens
MeSHD019108
THH1.00.01.1.02007
FMA67397
Anatomical terminology

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