The UCL Prize Lecture in Life and Medical Sciences (previously UCL Prize Lecture in Clinical Science) is a prize awarded annually by University College London since 1997. The prize lecture has become the pre-eminent series on contemporary science in Europe and the annual lecture provides an opportunity to debate and celebrate important scientific advancements.

This article relies largely or entirely on a single source. (July 2013)

• 1997 Klaus Rajewsky
• 1998 Joseph L. Goldstein (Nobel Prize in Medicine 1985)
• 1999 Stanley B. Prusiner (Nobel Prize in Medicine 1997)
• 2000 James Watson (Nobel Prize in Medicine 1962)
• 2001 Judah Folkman
• 2002 J. Craig Venter
• 2003 Sydney Brenner (Nobel Prize in Medicine 2002)
• 2004 Robert Weinberg (Woolf Prize 2004)
• 2005 Richard Axel (Nobel Prize in Medicine 2004)
• 2006 Harold Varmus (Nobel Prize in Medicine 1989)
• 2007 Tadataka Yamada
• 2008 Susumu Tonegawa (Nobel Prize in Physiology or Medicine 1987) ^[1]
• 2009 Martin Evans (Nobel Prize Physiology or Medicine 2007)^[2]
• 2010 Barry Marshall (Nobel Prize in Medicine 2005)^[3]
• 2011 Roger Tsien (Nobel Prize in Chemistry 2008)^[4]
• 2012 Jeffrey Friedman (Albert Lasker Award 2010)^[5]
• 2013 Gary Ruvkun (Louisa Gross Horwitz Prize 2009)
• 2014 Anthony W. Segal^[6]
• 2015 Sir John Gurdon (Nobel Prize in Physiology or Medicine 2012) ^[7]
• 2016 Françoise Barré-Sinoussi (Nobel Prize in Physiology or Medicine 2008)^[8]
• 2017 Patrick Vallance^[9]
• 2018 James P. Allison^[10] (Nobel Prize in Physiology or Medicine 2018)
• 2019 Jennifer Doudna (Nobel Prize in Chemistry 2020)
• 2020 Ann Graybiel^[11]

• List of medicine awards
• List of prizes named after people