Three ships of the United States Navy have been named USS O’Bannon, after the early Marine Corps hero Presley O'Bannon (1784–1850), hero of the Battle of Derna.

• The first USS O'Bannon (DD-177) was a Wickes-class destroyer, launched in 1919 and struck in 1936.
• The second USS O'Bannon (DD-450) was a Fletcher-class destroyer, launched in 1942 and struck in 1970. She received the Presidential Unit Citation and earned 17 battle stars for World War II service, more than any other destroyer in the war.
• The third USS O'Bannon (DD-987) was a Spruance-class destroyer, launched in 1978 and struck in 2005.

This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.