Ueli_Aebi
Ueli Aebi
Swiss structural biologist
Ueli Aebi is a Swiss structural biologist and co-founder[1] of the Maurice E. Müller Institute for Structural Biology at the Biozentrum University of Basel.
Ueli Aebi | |
|---|---|
Ueli Aebi (2012) | |
| Born | |
| Nationality | Swiss |
| Known for | Integrative structural biology |
| Scientific career | |
| Fields | Structural Biology |
| Institutions | University of Bern, Maurice E. Müller Institute for Structural Biology, University of Basel |
Aebi studied physics, mathematics, and molecular biology at the Universities of Bern and Basel from 1967 to 1974, graduating in 1977 in biophysics at the University of Basel. After establishing his academic career in the United States (University of California, Los Angeles, Johns Hopkins University School of Medicine), in 1986 he returned to the Biozentrum as professor of structural biology. He was co-founder of the Maurice E. Müller Institute for Structural Biology and its director from 1986 until reaching emeritus status in 2011.[2][3]
Aebi is recognized as a pioneer in integrative structural biology as well as mechano- and nanobiology.[4][5] His work focused on the elucidation of the structure, function and assembly of the cyto- and nucleoskeleton and the nuclear pore complex (NPC), as well as the amyloid fibrils that are a hallmark of Alzheimer's disease.[6] He studied the architecture of diverse supramolecular assemblies using a combination of light, electron and atomic force microscopy, X-ray crystallography, and protein engineering.[7] Among others, Aebi determined the 3-dimensional structure of the NPC by cryo-electron tomography.[8]
- 1993 Elected Member of the European Molecular Biology Organization
- 1999 Elected Member of the Academia Europaea
- 2007 Dr. honoris causa (h.c.) from the 1st Medical Faculty, Charles University, Prague, Czech Republic[9]
- 2011 Carl Zeiss Lecture Award of the German Society for Cell Biology[10]
- 2011 Distinguished Scientist Award of the Microscopy Society of America[11]
- Müller SA, Engel A (January 2012). "Looking back at a quarter-century of research at the Maurice E. Müller Institute for Structural Biology". J. Struct. Biol. 177 (1): 3–13. doi:10.1016/j.jsb.2011.11.013. PMID 22115996.
- "Journal of Nanobiotechnology". BioMed Central.
- "Prof. Dr. Ueli Aebi, Emeritus". biozentrum.unibas.ch.
- Coulombe, Pierre A. (2017). "The Molecular Revolution in Cutaneous Biology: Keratin Genes and their Associated Disease: Diversity, Opportunities, and Challenges". Journal of Investigative Dermatology. 137 (5). sciencedirect.com: e67–e71. doi:10.1016/j.jid.2016.04.039. PMC 5509967. PMID 28411849.
- "BioMed Central, Profile Ueli Aebi". biomedcentral.com/. Retrieved 2014-01-07.
- "MBI Scientific Advisory Board". mbi.nus.edu.sg/. Retrieved 2014-01-07.
- "EURO-Laminopathies project, Team Ueli Aebi". mfpl.ac.at/. Retrieved 2014-01-07.
- "Academy of Sciences of the Czech Republic, Biographical Sketch of Ueli Aebi" (PDF). nucleus.img.cas.cz/. Retrieved 2014-01-07.
- Webpage Biozentrum, Emeriti
- Lim RY, Herrmann H (January 2012). "From structural architecture to cellular organization: celebrating the scientific contributions of Ueli Aebi on the occasion of his retirement". J. Struct. Biol. 177 (1): 1–2. doi:10.1016/j.jsb.2011.12.011. PMID 22227641.