He then moved on to Alexandria, for whom he made his Serie A debut on 22 September 1935. He played in the cup final played in Genoa on 11 June 1936, but his side lost against Turin. He then moved to S.S. Lazio in 1936 for a joint fee of 400,000 lira, along with teammates Luigi Milano and Giovanni Riccardi.
He made his debut on 13 September 1936 in a 3–0 victory over A.C. Milan. The club finished in second place in the final standings, three points behind champions Bologna. He was the fifth most prolific goalscorer with fifteen goals that year. The following years were less positive for the biancoazzurri; an eighth place in the championship was followed by a ninth-place finish in 1938–39. In his early years in Rome he invariably started matches, missing only a few games, the majority due to a fractured collarbone.
He moved to Napoli in 1940 and the Neapolitan side finished the 1940–41 season in eighth place. The following year, Busani was the club's top scorer, but Napoli succumbed to relegation, despite some memorable victories against Milan and Juventus. The 1942–43 season, Napoli's first in Serie B, saw him play all the games and score 10 goals (the team's third top scorer), but this was not enough to bring the team promotion.
After the war he returned to Napoli and he finished as the club's top scorer in 1946–47 with 12 goals. The next season was negative for both Napoli and Busani, ending with the relegation back in Serie B; he played only 12 games and scored two goals, so decided to finish his career at Casertana.
After retiring, Busani settled in Campania, where he ran a sports shop and coached local sides.
- Carratelli. p. 80. Missing or empty
- Chievo lorenzograssi.it
- A SMALL COMPANY FOR A GREAT FOOTBALL DREAMS itcpasolivr.it
- Charles F. Church. Time for the old graysquare, by "Soccer 2000" - February 2002, pg. 68.
- Italy 1936-1937 rsssf.com
- Italy 1937-1938 rsssf.com
- Italy 1938-1939 rsssf.com
- Italy 1946-1947 rsssf . com
- Lacco Ameno from its origins to 1970 of Peter Ferrandino larassegnadischia.it