The United States attorney for the Districts of Guam and the Northern Mariana Islands is responsible for representing the federal government in civil and criminal litigation before the United States territorial courts of the District Court of Guam, whose jurisdiction is the Territory of Guam,^[1] and the District Court for the Northern Mariana Islands, whose jurisdiction is the United States Commonwealth of the Northern Mariana Islands (CNMI),^[2] encompassing the main islands of Saipan, Tinian and Rota as well as the mostly uninhabited "Northern Islands" of the Commonwealth.

Although the Territory of Guam and the CNMI are separate political entities and federal judicial districts, since 1978 the law has authorized the appointment of one United States attorney to serve both.^[3] This situation is unique within the entire United States.

The U.S. attorney maintains offices in Hagåtña, Guam and in Gualo Rai, Saipan.

• James G. Mackey: 1950 - 1952*^[4]
• John P. Raker: 1952 - 1954*
• Herbert G. Homme, Jr.: 1954 - 1962*
• James Pace Alger: 1962 - 1969*
• Duane K. Craske: 1969 - 1975*
• Ralph F. Bagley: 1975 - 1977*
• David T. Wood: 1977 - 1986
• K. William O'Connor: 1986 - 1989
• D. Paul Vernier: 1989 - 1991
• Frederick A. Black: 1991 - 2003
• Leonardo Matias Rapadas: June 2003 - June 2010
• Alicia Anne Garrido Limtiaco: 21 June 2010 - 10 March 2017
• Shawn N. Anderson: 4 January 2018 - present

 *Prior to 1978, incumbents did not hold both offices, as the latter had not been created.

• District Court of Guam
• District Court for the Northern Mariana Islands