VDU may stand for:

• VDU, a self contained attitude control thruster block (Russian: ВДУ) on space station Mir
• Federation of Independents (German: Verband der Unabhängigen), German nationalist political party in Austria active from 1949 to 1955
• Vacuum distillation unit, a processing unit in an oil refinery
• Video display unit, a synonym for a type of computer monitor
• Visual display unit, an electronic visual display
• Vytautas Magnus University (Lithuanian: Vytauto Didžiojo Universitetas) in Kaunas, Lithuania

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• Vudu

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