VRK2

VRK2

VRK2

Protein-coding gene in the species Homo sapiens

Serine/threonine-protein kinase VRK2 is an enzyme that in humans is encoded by the VRK2 gene.[5]

Quick Facts Available structures, PDB ...

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, leukocytes, fetal liver, and carcinomas. Its protein localizes to the endoplasmic reticulum and has been shown to phosphorylate casein and undergo autophosphorylation.

While several transcript variants may exist for this gene, the full-length nature of only one has been biologically validated to date.[5]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000028116 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000064090 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: VRK2 vaccinia related kinase 2".

Further reading


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This article uses material from the Wikipedia article VRK2, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.