Vanessa E. Wyche is an American engineer and civil servant who is currently serving as the Director of NASA’s Johnson Space Center (JSC) since 2021.^[1] A NASA employee for over 30 years, Wyche served previously as both Deputy Director of JSC and Lead Engineer. ^[2][3][4]

Wyche became interested in science at an early age and had parents who supported her interests in science.^[5][6] She grew up in Conway, South Carolina.^[6] When she was a junior in high school, she attended the Governor's School for top students.^[6] In 1981, she started attending Clemson University.^[6] Wyche holds a Bachelor’s of Science degree in Materials Engineering and a Master’s of Science in Bioengineering from Clemson.^[7]

Wyche began her career at the Food and Drug Administration.^[7] Her career with NASA began in 1989.^[7] Wyche also served as a Project Manager within the Space and Life Sciences Directorate, where she was responsible for the development and use of suites of hardware systems for medical and microgravity experiments on the space shuttle and the International Space Station.^[7][8] She has led a team of 400 engineers and scientists that are working on how to send human explorers to Mars.^[9] She has also worked as the director of the Exploration Integration and Science Directorate at the Johnson Space Center. On August 8, 2018, Vanessa Wyche was selected as the Johnson Space Center Deputy Director.^[2] The Johnson Space Center is home to America's astronaut corps, Mission Control Center, International Space Station mission operations, Orion and Gateway programs, and future space developments.^[10] Wyche is responsible for a range of human spaceflight activities, which includes development of human spacecraft, NASA astronaut selection and training, and mission control.^[11] She oversees commercialization of low-Earth orbit, and leads the Johnson Space Center's role in exploring the Moon and Mars with NASA's Artemis spacecraft.^[12] With Wyche serving as the director for Johnson Space Center, Johnson was recognized by Forbes and Statista as the Number 1 best employer among Texas' major employers.^[13]

Wyche has received the following awards:

• NASA Outstanding Leadership Medal^[14]
• Two NASA Achievement Medals^[14]
• Rotary Stellar Nomination
• Women@NASA Awardee (2014)^[7]
• “Women Worth Watching” honoree (2016)^[15]
• Inducted into Thomas Green Clemson Academy of Engineers and Scientists at Clemson University (2019)

Wyche is married to George Wyche Jr. Esq.,^[1] has one son,^[1] and currently lives in Houston.^[4]