"Word Up!" is a funk and R&B song originally recorded by American funk band Cameo in 1986. It was released as the first single from their thirteenth album of the same name. The song was written by band members Larry Blackmon and Tomi Jenkins. Its frequent airing on American dance, R&B, and contemporary hit radio, as well as its MTV music video (in which LeVar Burton appears as a police detective trying to arrest the band),^[3] helped the single become the band's best known hit.

The song is in A major with a metronome of 112 BPM, but the chorus shifts to F-sharp minor (the relative minor key of A major).^[4]

"Word Up!" was Cameo's first US Top 40 hit, peaking at number six on the Billboard Hot 100 and spending three weeks at number one on the Billboard R&B chart^[5] and one week at number one on the Billboard Hot Dance Singles chart.

In the United Kingdom, "Word Up!" spent ten weeks in the top 40 of the UK Singles Chart, peaking at number three on September 21, 1986 – for the week ending date September 27, 1986.

Besides being a commercial success, the track also earned critical acclaim from several publications. "Word Up!" won Cameo the Soul Train Music Award for Best R&B/Soul Single as well as the NME Award for Best Dance Record. Like the band's previous single "Single Life", "Word Up!" features a reference to the opening notes of Ennio Morricone's theme to The Good, the Bad and the Ugly.

"Word Up" was a colloquialism, popular in New York City and other US urban areas, that acted as an affirmation of what was said—a kind of a more-hip "You Bet".

Blackmon said of the song:

It just sounded good, and it was before its time. You can play "Word Up" anyplace anywhere, and someone is going to be grooving and bobbing their head. Our sound was unique, as well. I haven't heard another one like it, and we probably won't hear another one like it in the future. It was that significant for us.^[6]

Time Out listed the song number 54 in their The 100 best party songs list in 2018.^[7]

"Word Up!" has been covered numerous times by other artists. It is an easy song to sing, being riff-based and having a simple vocal melody.^[8]

In the 1990s, "Word Up!" was first covered by Scottish hard rock band Gun, whose version carried a harder, more rock-oriented sound, including a guitar solo.^{[citation needed]} Taken from their album Swagger, it was released on July 1, 1994, and peaked number eight on the UK Singles Chart.^[32] Two versions of the CD single were released in the UK, each carrying different cover art and different tracks.^[33]

"Word Up" was covered by British singer Melanie "Mel B" Brown of the Spice Girls—known as Melanie G at that time (and her only single under that name), as she was married to one of the Spice Girls's "Spice Boy" dancers, Jimmy Gulzar—as part of the film soundtrack to Austin Powers: The Spy Who Shagged Me. Produced by Rodney Jerkins, the song was released in the UK and Europe on 28 June 1999, and peaked at number 13 on the UK Singles Chart. The single was also included on the Japanese edition of Melanie’s album Hot. Static sings uncredited background vocals on the track.^[45] Brown's bandmate Emma Bunton sings background vocals on the B-side "Sophisticated Lady", with an uncredited rap by Dexter.

The music video, which features Verne Troyer (the Mini-Me actor in the Austin Powers films), was predominantly filmed with the use of green screen, and takes places in a black-and-white, highly animated and complex world. Melanie's character is part evil queen, part dominatrix, her style drawing comparisons to Grace Jones. However, some of the imagery in the video was deemed to be too dark and sexually suggestive, as well as scary, for minors to be exposed to;^{[by whom?]} one scene, for example, portrayed Melanie lying down nude, with a heart covering her private area. Another shows Verne Troyer "polishing" her buttocks like a window-cleaner. Near the end of the video, a child can be seen wearing a dress with the word "Phagocyte" on it. Overall, it was the heavy and potentially scary fantasy imagery that garnered a second version to be made, featuring Melanie in a blue-metallic setting wearing shining, gem-like outfits. The original video was then limited to being played only after-midnight on MTV Europe and MTV UK, among other networks.

"Word Up!" by American nu metal band Korn is a cover of the Cameo song. Its musical arrangements are similar to that of the cover version by Gun, except it is played in a lower sounding 7 string guitar tuning instead of the standard E.^{[citation needed]} "Word Up!" was the first track featured on Korn's 2004 retrospective album, Greatest Hits, Volume 1, and was one of two new tracks along with Pink Floyd's "Another Brick in the Wall" that was exclusive to the album (the "Word Up!" CD single also featured a live performance of the latter).

In 2007 German singer Jan Delay recorded a mashup of the music from "Word Up!" with the lyrics of Das Bo's "Türlich, Türlich (Sicher, Dicker)". The new song was titled "Türlich Türlich (Word Up)" and was a hit in German-speaking countries.

British girl group Little Mix released a cover version of the song for Sport Relief 2014, through Syco Music and Columbia Records. It was released digitally on March 16, 2014, followed by a physical release the following day, which was only available to purchase from Sainsbury's supermarkets.^[71]

"Word Up!" peaked at number six on the UK Singles Chart and reached the top twenty in Ireland. The song also charted in Australia, Austria, Denmark, France, Czech Republic, and Japan. It has been certified gold in Brazil. The single is also included on the expanded edition of the group's second studio album Salute (2013).