The ZINC database (recursive acronym: ZINC is not commercial) is a curated collection of commercially available chemical compounds prepared especially for virtual screening. ZINC is used by investigators (generally people with training as biologists or chemists) in pharmaceutical companies, biotechnology companies, and research universities.

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ZINC database

Content
Description	Chemical database
Data types captured	Commercially available and annotated small molecules for virtual screening
Contact
Research center	University of California San Francisco
Laboratory	Irwin Lab   Shoichet Lab
Authors	John Irwin, Brian Shoichet, and a cast of several
Primary citation	PMID 26479676
Release date	2004
Access
Website	ZINC
Miscellaneous
License	ZINC is free to use for everyone. Redistribution of significant subsets requires written permission from the authors.
Versioning	ZINC15
Data release frequency	continuously updated; static subsets regenerated quarterly or better.
Curation policy	continuously curated

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ZINC is different from other chemical databases because it aims to represent the biologically relevant, three dimensional form of the molecule.

ZINC is updated regularly and may be downloaded and used free of charge. It is developed by John Irwin in the Shoichet Laboratory in the Department of Pharmaceutical Chemistry at the University of California, San Francisco.

The latest release of the website interface is "ZINC 15" (2015). The previous website was at ZINC, but the maintainers recommend moving to ZINC15 because of its better search capabilities. The database contents are continuously updated.

• PubChem a database of small molecules from the chemical and biological literature, hosted by NCBI
• ChEMBL, a database of information about medicinal chemistry and biological activities of small molecules.

• ZINC database