The 1983 Major League Baseball All-Star Game was the 54th edition of the midsummer classic between the all-stars of the American League (AL) and National League (NL), the two leagues comprising Major League Baseball. The game was held on July 6 at Comiskey Park in Chicago, Illinois, the home of the Chicago White Sox of the American League.^[1] The Wednesday night game resulted in a 13–3 American League victory.^[2] The game celebrated the fiftieth anniversary of the All-Star Game,^[1] and occurred exactly 50 years to the date of the first All-Star game, also at Comiskey Park. This was the 54th game, as no game was held in 1945, while two were held each year from 1959 through 1962.

This was the fifth All-Star Game played in Chicago, and the third to be hosted by the White Sox at Comiskey Park (1933, 1950), with two by the Chicago Cubs at Wrigley Field (1947, 1962). This was the last time the All-Star Game was played in the venue where the annual exhibition began. When the White Sox next hosted the All-Star Game twenty years later in 2003, they had moved across the street to their new home at U.S. Cellular Field.

The game was the first American League win in twelve years, and only the second AL win since 1962.^[2] The thirteen runs scored by the American League set a new record for one team in All-Star Game history. The ten-run margin of victory was the largest since the 12–0 American League victory in 1946.

The game is perhaps best remembered for Fred Lynn's grand slam off Atlee Hammaker of the Giants, part of a big third inning for the home team. As of 2024, it is still the only grand slam in the history of the Midsummer Classic. During that third inning, the American League set All-Star Game records for the most hits (6) and runs (7) by a single team in their half-inning - all off Hammaker.^[3][4]

Prior to the first pitch, Chuck Mangione played the Canadian national anthem on his flugelhorn, while the Oak Ridge Boys sang the Star-Spangled Banner. The colors were presentated by the Great Lakes Naval Training Center Color Guard, which previously presented at the 1947, 1950, and 1963 games; they did the honors again in 1990 and 2003.

For this golden anniversary, there was also an "Old Timer's Game" played on Tuesday, the day before the All-Star game.^[1] Because Independence Day was on Monday this year, the All-Star break did not begin until that evening, as the holiday included a full slate of day games.^[5]

Players in italics have since been inducted into the National Baseball Hall of Fame.