The 2008 Bank of America 500 was a NASCAR Sprint Cup Series stock car race held on October 11, 2008 at Lowe's Motor Speedway in Concord, North Carolina. The race was the thirty-first race of the 2008 NASCAR Sprint Cup season and fifth of the Chase for the Sprint Cup, serving as the only Saturday night race in the Chase as of 2008. The 334-lap, 501 miles (806 km) race was televised on ABC. The race's television broadcast began at 7 pm ET, and the Performance Racing Network along with Sirius Satellite Radio had radio coverage starting at the same time.

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2008 Bank of America 500

Race details
Race 31 of 36 in the 2008 NASCAR Sprint Cup Series season
2008 Bank of America 500 program cover, featuring all 12 Chase drivers. Artwork by NASCAR artist Sam Bass. The painting is called "The Chase Is On!"
Date	October 11, 2008 (2008-October-11)
Official name	Bank of America 500
Location	Lowe's Motor Speedway, Concord, North Carolina
Course	Permanent racing facility 1.5 mi (2.414 km)
Distance	334 laps, 501 mi (806.281 km)
Average speed	133.699 miles per hour (215.168 km/h)
Pole position
Driver	Jimmie Johnson	Hendrick Motorsports
Time	2008 Owner's points
Most laps led
Driver	Jimmie Johnson	Hendrick Motorsports
Laps	67
Winner
No. 31	Jeff Burton	Richard Childress Racing
Television in the United States
Network	ABC
Announcers	Jerry Punch, Dale Jarrett and Andy Petree

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Jeff Burton earned his 21st and final Cup Series victory with this race.

• Patrick Carpentier was released from driving the No. 10 Gillett Evernham Motorsports Dodge after an argument with his team manager about his performance during time trials the week before at Talladega. Carpentier missed the race, despite being quicker than his teammates during practice. Mike Wallace was Carpentier's replacement for the race.

Because of rain, qualifying was canceled for the eighth time this season, and so the cars lined up by rulebook.