Bimakalim

Bimakalim
Names
	Preferred IUPAC name 2,2-Dimethyl-4-(2-oxopyridin-1(2H)-yl)-2H-1-benzopyran-6-carbonitrile
Identifiers
CAS Number	117545-11-6 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL12552;
ChemSpider	54683;
PubChem CID	60674;
UNII	4MP5GR4H9L ;
CompTox Dashboard (EPA)	DTXSID40151803 ;
	InChI InChI=1S/C17H14N2O2/c1-17(2)10-14(19-8-4-3-5-16(19)20)13-9-12(11-18)6-7-15(13)21-17/h3-10H,1-2H3 Key: JTVSKASWNROQQF-UHFFFAOYSA-N;
	SMILES CC1(C=C(c2cc(ccc2O1)C#N)n3ccccc3=O)C;
Properties
Chemical formula	C17H14N2O2
Molar mass	278.311 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Bimakalim

Chemical compound

Bimakalim is a potassium channel opener.^[1] It can be prepared from 2-acetyl-4-cyanophenol .^[2]

Quick Facts Names, Identifiers ...

Share this article:

This article uses material from the Wikipedia article Bimakalim, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[1] [1]
Puddu, Paolo Emilio; Garlid, Keith D; Monti, Francesco; Iwashiro, Katsunori; Picard, Sandra; Dawodu, Amos Adeyemo; Criniti, Anna; Ruvolo, Giovanni; Campa, Pietro Paolo (2006). "Bimakalim: A Promising KATP Channel Activating Agent". Cardiovascular Drug Reviews. 18: 25. doi:10.1111/j.1527-3466.2000.tb00031.x.

[2] [2]
Bergmann, Rolf; Gericke, Rolf (1990). "Synthesis and antihypertensive activity of 4-(1,2-dihydro-2-oxo-1-pyridyl)-2H-1-benzopyrans and related compounds, new potassium channel activators". Journal of Medicinal Chemistry. 33 (2). American Chemical Society (ACS): 492–504. doi:10.1021/jm00164a005. ISSN 0022-2623.

[1]

[2]

Bimakalim

References

Share this article: