Irbesartan
Irbesartan
Chemical compound
Irbesartan, sold under the brand name Aprovel among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease.[5] It is a reasonable initial treatment for high blood pressure.[5] It is taken by mouth.[5] Versions are available as the combination irbesartan/hydrochlorothiazide.[5][6][7]
Common side effects include dizziness, diarrhea, feeling tired, muscle pain, and heartburn.[5][8] Serious side effects may include kidney problems, low blood pressure, and angioedema.[5] Use in pregnancy may harm the baby and use when breastfeeding is not recommended.[9] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II.[5]
Irbesartan was patented in 1990, and approved for medical use in 1997.[10] It is available as a generic medication.[8] In 2021, it was the 172nd most commonly prescribed medication in the United States, with more than 3 million prescriptions.[11][12]