This is a list of adult animated web series. Works in this medium could be considered adult for any number of reasons, which include the incorporation of explicit or suggestive sexual content, graphic violence, profane language, dark humour, or other thematic elements inappropriate for children. Works in this genre may explore philosophical, political, or social issues. Some productions are noted for their complex and/or experimental storytelling and animation techniques. Adult animation is typically defined as animation which skews toward adults.^[1][2][3][4] It is also described as something that "formative youths should stay far, far away from"^[5] or has adult humor^[6][7] and comes in various styles,^{[8][9][10][11]} but especially sitcoms and comedies.^[12] These animations can also "appeal to wide swaths of viewers," including those aged 18–34.^[13][14] Adweek called adult animation "animated projects aimed at grown-ups, not kids."^[15]

This list does not include Japanese, Chinese, or Korean series, as it is much more common in these regions. It also does not include animated films or television series, including those on streaming video on demand platforms such as Netflix, Hulu, Amazon Prime Video, Max, Peacock, Disney+, Apple TV+, and Paramount+.^{[lower-alpha 1]}

• LGBT representation in American adult animation
• Modern animation in the United States
• Lists of animated feature films
• Independent animation
• Animation in the United States in the television era
• Cartoon violence