Masters of Science Fiction is a television anthology series by some of the producers of Masters of Horror. The show debuted on ABC on August 4, 2007, at 10PM for a run of four episodes.^[1] It was originally scheduled to run in six parts, but two episodes were removed from the schedule for undisclosed reasons.^[2] All six episodes can be streamed for free on Tubi and The Roku Channel, and purchased for viewing at Amazon Prime Video and Vudu.

The show follows a similar format as Masters of Horror, with each hour long episode taking the form of a separate short film adaptation of a story by a respected member of the science fiction community, hence the Masters in the title.^[2]

In December 2007, the show was picked up by Space in Canada. This was followed by the North American premiere of the missing two episodes. A Region 1 DVD of all six episodes was released on August 5, 2008. On February 12, 2012, the Science Channel began airing the episodes, under the title Stephen Hawking's Sci-Fi Masters, beginning with the first domestic airing of the episode "Watchbird".^[3]

The show is hosted off-screen by physicist Stephen Hawking.^[1]