Neuburg-Schrobenhausen is a Landkreis (district) in Bavaria, Germany. It is bounded by (from the east and clockwise) the districts of Pfaffenhofen, Aichach-Friedberg, Donau-Ries and Eichstätt, and by the city of Ingolstadt.

The district was established in 1972 by merging the former districts of Neuburg and Schrobenhausen.

The district consists of the previously swampy areas between the Danube and Paar rivers, that are called the Donaumoos. North of the Danube the district includes a small part of the Altmühl Valley Nature Park.

The coat of arms displays:

• the bear's head from the city arms of Schrobenhausen
• the heraldic lion of the Electorate of the Palatinate
• a wavy line symbolising the Danube River