Salesianum School is a Catholic independent school for boys located in Wilmington, Delaware. It is run independently within the Diocese of Wilmington and is operated by the Oblates of St. Francis de Sales.

The current enrollment is about 930 students, declining from a peak of about 1,100 in recent years, from Delaware, Maryland, New Jersey, and Pennsylvania. Salesianum has established a close connection with Lycée Saint Michel, another Oblate high school, located in Annecy, France.^{[citation needed]} Salesianum was named one of the Top 50 Catholic High Schools in America by the Catholic Honor Roll in 2004, 2007, 2008, 2009, and 2010.^{[3][4][5][6][7]}

The 22-acre (89,000 m²) campus is home to the school itself as well as a gymnasium. In addition to the campus, the athletic program also makes use of Wilmington's newly constructed Abessinio Stadium, formerly Baynard Stadium, which is located directly across from the school. In 2023, the school was given a $10 million donation by alumnus Anthony Fuscoto to build a new athletic facility.^[8]

Salesianum School has won 185 Delaware Interscholastic Athletic Association (DIAA) approved boys' state championships,^{[citation needed]} winning its first state championship in basketball in 2014^[9] and latest one in 2023.^[10]

Salesianum's historical rival is St. Mark's High School, which is located in suburban Wilmington. Their fall meeting in football is commonly referred to as "The Holy War".^[11][12]

The soccer team won 11 state championships between 2002 and 2014, and in 2013 defeated Saint Benedict's Preparatory School, the top ranked high school program in the nation, on a game-winning goal scored by Joseph Dolce. They finished the season ranked as the number two high school team in the country.^[13] The 2016 soccer team finished the season ranked sixth in the nation by USA Today on its final Super 25 Expert Rankings.^[14]

The cross country team has won 37 of the 42 DIAA state boys' championships, losing only five years between 1972 and 2013.^[15]

The Salesianum swimming team has won ten consecutive state boys' championships between 2005 and 2015, and 11 of 12 from 2005-2017.^[16]

Salesianum (Latin for "House of Sales", referring to St. Francis de Sales) was founded in 1903 and was located at 8th and West Streets until the move to its current location in 1957. In 1950, Rev. Thomas Lawless, OSFS, a 1908 graduate of Salesianum, admitted five African American students four years prior to the Brown v. Board of Education decision which made it mandatory, thus making Salesianum the first racially integrated school in the state of Delaware. The school was recognized for this with a historical marker.^[17]

In August 2012, the Wilmington/Philadelphia Province of the Oblates of St. Francis de Sales published a letter stating, "Since 2004, the Wilmington/Philadelphia Province of the Oblates of St. Francis de Sales has been named in lawsuits in the Superior Court of Delaware filed by 40 plaintiffs, each of which contained allegations of sexual abuse of a minor." The letter named 12 oblates who had been involved and expressed regrets, stating, "The abuse of children by priests and other clergy is shocking, reprehensible, and devastating to all whose trust has been shattered by their selfish deeds."^[18] This followed a settlement in August 2011 of 39 lawsuits against the school and the order, with the order and its insurers paying $24.8 million to be shared between the plaintiffs.^[19]

• David Acord (1989): Emmy award winning sound editor^[20]
• Miguel Bezos (1963): father of Jeff Bezos^[21]
• Hugh T. Broomall (1966): United States Air Force Major General^[22]
• John M. Byrne, Ph.D. (1967): Distinguished Professor of Energy and Climate Policy at the University of Delaware. Contributed to Working Group III of the United Nations-sponsored Intergovernmental Panel on Climate Change (IPCC) since 1992. The panel was awarded the 2007 Nobel Peace Prize.^[23][24][25]
• Joe Campbell (1973): NFL player, Super Bowl champion (XV)
• Neil Casey (2000): actor and writer^{[citation needed]}
• Christopher Castellani (1990): novelist
• Steve Casula (2005): NCAA football coach^[26]
• Paul Anthony Ciancia: terrorist shooter at Los Angeles International Airport in 2013^[27]
• Cesidio Colasante (1993): NPSL midfielder^{[citation needed]}
• James J. Connell (1957): Lieutenant commander in the United States Navy, recipient of the Navy Cross, Delaware Aviation Hall of Fame inductee^[28]
• Joseph diGenova (1963): United States Attorney for the District of Columbia (1983-1988)^[29]
• Donte DiVincenzo (2015): NBA player and 2021 NBA Champion with the Milwaukee Bucks^[30]
• William M. Duffy (1936): served as the President Judge of the Delaware Superior Court, the Chancellor of the Court of Chancery, and later as a Justice on the Delaware Supreme Court; co-author of The Supreme Court Until 1951: The "Leftover Judge" System and The Supreme Court of Delaware After 1951: The Separate Supreme Court^[31][23]
• Charles J. Dunlap Jr. (1968): Major General, United States Air Force; professor at Duke University law school^{[citation needed]}
• James V. Fiorelli (1958): Colonel, United States Air Force, Delaware Aviation Hall of Fame inductee^[32]
• F. Gregory Gause III (1976): Professor of International Affairs and Head of the International Affairs Department at the Bush School of Government and Public Service at Texas A&M.^{[33] [23]}
• Edgar Johnson; University of Delaware swimming and cross country coach and long serving Athletic Director from 1984-2009.^[34]
• David J. Kelly (1995): screenwriter^[35]
• Pat Kenney: professional wrestler^[36]
• Albert "Jim" Madora (1964): Major General, United States Army^[37]
• Stephen Mallozzi (2019): NASCAR Camping World Truck Series driver^[38]
• Bill Marsilii (1980): screenwriter^{[citation needed]}
• Charlie McDermott (attended for two years, left in 2006): actor^{[citation needed]}
• Bernie McInerney (1954): actor^{[citation needed]}
• Anthony Monaco, M.D., Ph.D. (1977): geneticist, President of Tufts University^[39]
• Brian O'Neill (2014): NFL offensive lineman^[40]
• Donald E. Pease (1963): Professor of English and comparative literature at Dartmouth College. Scholar on Dr. Seuss.^[23][41]
• Bill Press (1958): political commentator and talk radio host, chair of the California Democratic Party (1993–1996)^[42]
• Michael Reed (1990): NFL player, defensive back coach at Clemson University^[43]
• Troy Reeder (2014): NFL linebacker, Super Bowl champion (LVI)^[44]
• Kevin P. Reilly (1969): NFL linebacker^{[citation needed]}
• Edward J. Scully (1958): Lieutenant Colonel, United States Army, Delaware Aviation Hall of Fame inductee^[45]
• Andrew Szczerba (2007): NFL tight end
• Ken Szotkiewicz (1965): MLB shortstop^{[citation needed]}
• Timothy Szymanski (1980): United States Navy vice admiral^[46]
• John Tosi (c. 1933): NFL offensive lineman^[47]
• Francis D. Vavala (1965): United States Army Lieutenant General and adjutant general for Delaware
• Tom Welling (attended as a freshman in 1992): actor^{[citation needed]}
• Victor Zwolak (1956): 1964 Olympic runner^[48]