Tetramethylsuccinonitrile

Tetramethylsuccinonitrile

Tetramethylsuccinonitrile

Chemical compound

Tetramethylsuccinonitrile or TMSN is an organic compound with the formula (C(CH3)2CN)2, classified as a dinitrile. It is a colorless and odorless solid. TMSN is the byproduct from the use of some radical initiators used in polymer manufacture.[6]

Quick Facts Names, Identifiers ...

TMSN is derived from 2,2'-azobis-isobutyronitrile:

(NC(CH3)2CN)2 → (C(CH3)2CN)2 + N2

AIBN is a common radical initiator in the manufacture of polyvinyl chloride polymers.

Safety considerations

Because PVC is pervasive and can contain TMSN, the safety aspects of this dinitrile has generated interest.[7]

Symptoms of large or short exposure to this substance include convulsions, dizziness, headache, nausea, vomiting or even unconsciousness, hence affects central nervous system.

In regards to occupational exposures, the U.S. Occupational Safety and Health Administration and the U.S. National Institute for Occupational Safety and Health have set limits for dermal exposure at 3 mg/m3 over an eight-hour time-weighted average.[3]

References

  1. [1]
    "TETRAMETHYL SUCCINONITRILE". International Chemistry Safety Cards. ILO and WHO. Retrieved 27 November 2023.
  2. [2]
    "Tetramethyl succinonitrile". Royal Society of Chemistry. Retrieved 21 October 2015.
  3. [3]
    "Tetramethyl succinonitrile". NIOSH Pocket Guide to Chemical Hazards. Centers for Disease Control and Prevention. Retrieved 15 November 2013.
  4. [4]
    NIOSH Pocket Guide to Chemical Hazards. "#0604". National Institute for Occupational Safety and Health (NIOSH).
  5. [5]
    "Tetramethyl succinonitrile". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  6. [6]
    Polymeric Materials Encyclopedia, Joseph C. Salamone, 1996, CRC Press, ISBN 0-8493-2470-X
  7. [7]
    Ishiwata, H; Inoue T; Yoshihira K. (July 1987). "Tetramethylsuccinonitrile in polyvinyl chloride products for food and its release into food-simulating solvents". Zeitschrift für Lebensmittel-Untersuchung und -Forschung. 185 (1): 39–42. doi:10.1007/BF01083339. PMID 3617937. S2CID 2337990.
Share this article:

This article uses material from the Wikipedia article Tetramethylsuccinonitrile, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.