Tris(2-chloroethyl)_phosphate
Tris(2-chloroethyl) phosphate
Chemical compound
For the reducing agent frequently used in biochemistry and molecular biology applications, see TCEP.
Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.[2]
Quick Facts Names, Identifiers ...
| Names | |
|---|---|
| Preferred IUPAC name
Tris(2-chloroethyl) phosphate | |
| Other names
2-Chloroethanol phosphate; Tris(β-chloroethyl) phosphate; Tri(2-chloroethyl) phosphate; Tris(2-chloroethyl) orthophosphate; TCEP | |
| Identifiers | |
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3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.003.744  |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C6H12Cl3O4P | |
| Molar mass | 285.48 g·mol−1 |
| Density | 1.39 g/mL[1] |
| Boiling point | 192 °C (378 °F; 465 K) 10 mmHg[1] |
| Hazards | |
| GHS labelling: | |
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| Danger | |
| H302, H351, H360, H411 | |
| P201, P202, P270, P273, P301+P312, P308+P313, P391 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Because of its suspected reproductive toxicity, it is listed as a substance of very high concern under the European Union's REACH regulations. Its use has been largely replaced by tris(chloropropyl) phosphate, which is safer.[3]
- "Tris(2-chloroethyl) phosphate". Sigma-Aldrich. Retrieved February 25, 2013.
- Opinion on tris(2-chloroethyl)phosphate (TCEP) in Toys (PDF) (Report). European Commission, Scientific Committee on Health and Environmental Risks. 22 March 2012. Retrieved February 25, 2013.
- Krivoshiev, Boris V.; Beemster, Gerrit T.S.; Sprangers, Katrien; Blust, Ronny; Husson, Steven J. (April 2018). "A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects". Journal of Applied Toxicology. 38 (4): 459–470. doi:10.1002/jat.3553. PMID 29143341. S2CID 3320347.