ʻAnaseini Takipō Afuhaʻamango (1 March 1893 – 26 November 1918) was Queen of Tonga from 1909 to 1918 as the second wife of George Tupou II. Her name was also often rendered as Ana Seini Takipo.^[1]

ʻAnaseini Takipō Afuhaʻamango was born on 1 March 1893 in Nukuʻalofa. Her father was Tēvita Ula Afuhaʻamango, Noble of Vavaʻu, and her mother was Siosiana Tongovua Tae Manusā. From her maternal relation, she was a descendant of the Tuʻi Kanokupolu line. King George Tupou II had rejected her half-sister ʻOfakivavaʻu in 1899 to marry Lavinia Veiongo, a choice that damaged the royal family's relation with the rest of the country and nearly caused a civil war between factions loyal to the family of ʻOfa and the family of Lavinia. Both women died in 1901 and 1902 respectively and the grief-strickened king remained unmarried with only one legitimate daughter Princess Sālote Mafile‘o Pilolevu, who was an unpopular heir with the former supporters of the deceased ʻOfa.^[2][3]

In order to appease his subjects and the Council of Chiefs, King Tupou II married ʻAnaseini Takipō, the sister of the rejected ʻOfa, on 11 November 1909. She was sixteen years old at the time of the marriage. It was expected that the King would be able to produce a male heir to succeed him to the throne. Queen Lavinia's daughter Princess Sālote was sent Auckland, New Zealand, as a form of exile.^[4][3][1]

Queen Takipō gave birth to two daughters: ʻElisiva Fusipala Taukiʻonelua (1911–1911, known as Princess ʻOnelua) and ʻElisiva Fusipala Taukiʻonetuku (1912–1933, known as Princess Fusipala). Princess ʻOnelua died of convulsion in her infancy and Princess Fusipala died in Australia unmarried.^[5][1]

Her husband died on 5 April 1918 and was succeeded by his eldest daughter, who became Queen Sālote Tupou III, the first queen regnant of Tonga.^[6][7] Shortly after, Queen Dowager Takipō died at Finefekai, Nukuʻalofa, on 26 November 1918, as a result of the infamous 1918 flu pandemic which killed eight percent of the population of Tonga.^[1] After Takipō's death, Sālote assumed the guardianship of her half-sister Princess Fusipala.^[8][9][10] She was buried at Malaʻeʻaloa, the chiefly burial ground in Kolomotuʻa, instead of Malaʻekula where her husband and daughters were buried.^[11]