(S)-corytuberine_synthase

(S)-corytuberine synthase

(S)-corytuberine synthase

Enzyme

(S)-corytuberine synthase is a cytochrome P450 enzyme purified from the plant Coptis japonica (Japanese goldthread),[1] with EC number EC 1.14.19.51 and CYP Symbol CYP80G2 (Cytochrome P450, family 80, member G2), and catalyses an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis.[2]

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References

  1. [1]
    Ikezawa N, Iwasa K, Sato F (April 2008). "Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells". The Journal of Biological Chemistry. 283 (14): 8810–21. doi:10.1074/jbc.M705082200. PMID 18230623.
  2. [2]
    Meelaph T, Kobtrakul K, Chansilpa NN, Han Y, Rani D, De-Eknamkul W, Vimolmangkang S (August 2018). "Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine". ACS Omega. 3 (8): 8794–8802. doi:10.1021/acsomega.8b00827. PMC 6644620. PMID 31459012.


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