16β-Hydroxyestrone

16β-Hydroxyestrone

16β-Hydroxyestrone

Chemical compound

16β-Hydroxyestrone (16β-OH-E1) is an endogenous estrogen which serves as a metabolite of estrone as well as a metabolic intermediate in the transformation of estrone into epiestriol (16β-hydroxyestradiol).[1][2] 16β-Hydroxyestrone has similar estrogenic activity to that of 16α-hydroxyestrone.[2] It is less potent than estradiol or estrone but can produce similar maximal uterotrophy at sufficiently high doses, suggesting a fully estrogenic profile.[2]

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See also

References

  1. [1]
    "16beta-Hydroxyestrone". PubChem.
  2. [2]
    Velardo, Joseph Thomas (1964). The Actions of Steroid Hormones on Estradiol-17β in Uterine Growth and Enzymorphology. Hormonal Steroids Biochemistry, Pharmacology, and Therapeutics. pp. 463–490. doi:10.1016/B978-0-12-395506-7.50065-0.



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