The 1972 Trans-American Championship was the seventh running of the Sports Car Club of America's Trans-Am Series. The first seven rounds used split classes, while the last four rounds had the Under 2500cc class only. Milt Minter brought Pontiac its first win, at Mid-Ohio. George Follmer and American Motors won the over 2.5L division, while John Morton led Datsun to the championship title of the "Two-Five Challenge".

1972 is considered to be the end of the series' "golden era". From 1973 onward, Trans Am would evolve into a lesser clone of the rival IMSA GT Championship, with similarly modified cars, but with a more conventional focus with vehicles such as the Chevrolet Beretta being used. IMSA GT's focus on exotic cars such as Ferraris and Porsches provided a more adaptable format, in comparison to Trans Am's reliance on domestic performance sedans.

• 1972 Can-Am season