The 2006 NFL season was the 87th regular season of the National Football League (NFL). Regular season play was held from September 7 to December 31, 2006.

Patriots

Bills

Dolphins

Jets

Bengals

Ravens

Steelers

Browns

Colts

Titans

Jaguars

Texans

Broncos

Chiefs

Raiders

Chargers

AFC teams: West, North, South, East

Cowboys

Giants

Eagles

Redskins

Bears

Lions

Packers

Vikings

Falcons

Panthers

Saints

Buccaneers

Cardinals

Rams

Seahawks

49ers

NFC teams: West, North, South, East

The season began with the reigning Super Bowl XL champion Pittsburgh Steelers defeating the Miami Dolphins in the NFL Kickoff Game.

The NFL title was eventually won by the Indianapolis Colts, when they defeated the Chicago Bears in Super Bowl XLI at Dolphin Stadium at Miami Gardens, Florida on February 4, 2007.

On March 20, 2006, Paul Tagliabue announced his plans to retire as NFL commissioner. During an NFL meeting in Northbrook, Illinois, on August 8, league team owners selected Roger Goodell, the NFL's then-current chief operating officer, as the new commissioner. Tagliabue continued to serve as commissioner until Goodell officially replaced him on Friday September 1.

Tagliabue became NFL commissioner on October 26, 1989. During his tenure, the league added four new teams; saw four franchises move (including two franchises—the Rams and Raiders—from Los Angeles, the second-largest television market in the U.S.); the construction of seventeen new stadiums; began its own in-house television specialty cable network, the NFL Network; greatly increased television rights fees with its broadcasters, including the addition of the Fox network and its NFL programming; and maintained labor peace with the players' union.

The 2006 NFL Draft was held from April 29 to 30, 2006 at New York City's Radio City Music Hall. With the first pick, the Houston Texans selected defensive end Mario Williams from North Carolina State University.

Bernie Kukar and Tom White retired. Jerome Boger and Gene Steratore were promoted to referee.

• Jerry Azumah
• Ahmed Plummer
• Jimmy Smith
• Wayne Chrebet
• Dat Nguyen
• Tommy Maddox
• Jerome Bettis
• Curtis Martin
• Doug Flutie
• Deion Sanders
• Brady Smith
• Dez White
• Kordell Stewart

• End zone celebrations became more restricted. Players cannot celebrate by using any type of prop, or do any act in which they are on the ground. Players may still spike, spin the ball, or (until 2014), dunk it over the goal posts. Dancing in the end zone is also permitted as long as it is not a prolonged or group celebration. The Lambeau Leap, though, is still legal.^[1]
• Defenders were prohibited from hitting a passer in the knee or below unless they are blocked into him. This rule was enacted in response to the previous season's injuries to Cincinnati Bengals quarterback Carson Palmer, Pittsburgh Steelers' Ben Roethlisberger, and Tampa Bay Buccaneers' Brian Griese.
• Down-by-contact calls could now be reviewed by instant replay to determine if a player fumbled the ball before he was down, and who recovered it. Previously, these plays could not be reversed once officials blew the whistle.
• The "horse-collar tackle" rule enacted during the previous 2005 season was expanded. Players are now prohibited from tackling a ball carrier from the rear by tugging inside his jersey. Previously, it was only illegal if the tackler's hand got inside the player's shoulder pads.
• To reduce injuries, defensive players cannot line up directly over the long snapper during field goal and extra point attempts.

Within each conference, the four division winners and the top two non-division winners with the best overall regular season records) qualified for the playoffs. The four division winners are seeded 1–4 based on their overall won-lost-tied record, and the wild card teams are seeded 5–6. The NFL does not use a fixed bracket playoff system, and there are no restrictions regarding teams from the same division matching up in any round. In the first round, dubbed the wild-card playoffs or wild-card weekend, the third-seeded division winner hosts the sixth-seed wild card, and the fourth seed hosts the fifth. The 1 and 2 seeds from each conference received a first-round bye. In the second round, the divisional playoffs, the number 1 seed hosts the worst-surviving seed from the first round (seed 4, 5, or 6), while the number 2 seed will play the other team (seed 3, 4, or 5). The two surviving teams from each conference's divisional playoff games met in the respective AFC and NFC Conference Championship games, hosted by the higher seed. Although the Super Bowl, the championship round of the playoffs, is played at a neutral site, the designated home team is based on an annual rotation by conference.^[4]

The following teams and players set all-time NFL records during the regular season:

All-Pro Team

• Buffalo Bills – Dick Jauron; replaced Mike Mularkey, who resigned after the 2005 season
• Detroit Lions – Rod Marinelli; replaced interim head coach Dick Jauron who replaced Steve Mariucci who was fired following Thanksgiving Day during the 2005 season.
• Green Bay Packers – Mike McCarthy; replaced Mike Sherman
• Houston Texans – Gary Kubiak; replaced Dom Capers
• Kansas City Chiefs – Herman Edwards; replaced Dick Vermeil who retired following the 2005 season
• Minnesota Vikings – Brad Childress; replaced Mike Tice
• New Orleans Saints – Sean Payton; replaced Jim Haslett
• New York Jets – Eric Mangini; replaced Herman Edwards
• Oakland Raiders – Art Shell; replaced Norv Turner
• St. Louis Rams – Scott Linehan; replaced interim head coach Joe Vitt who replaced Mike Martz who was not allowed to coach due to health problems during the 2005 season.

• Arizona Cardinals: The Cardinals moved from Sun Devil Stadium in Tempe to University of Phoenix Stadium in Glendale, with the University of Phoenix acquiring the naming rights
• Miami Dolphins: Dolphins Stadium was renamed to the singular Dolphin Stadium
• The New Orleans Saints returned to their home at the Louisiana Superdome in Week Three. Due to damage by Hurricane Katrina, the Saints' first 2005 home game against the New York Giants was moved to Giants Stadium. The Saints then played their remaining 2005 home schedule at Baton Rouge's Tiger Stadium for four games and at San Antonio's Alamodome for three games.
• Tennessee Titans: The Coliseum was renamed LP Field after the manufacturing company Louisiana-Pacific (LP) acquired the naming rights

• The Minnesota Vikings added trim lines to the outside shoulders and sleeves, and the jersey sides and pants. The horn on the helmet was also modified to be slightly more defined. Purple pants were also worn at selected games.
• The New Orleans Saints began wearing black pants at selected games.

Through week 11 of the season, all NFL games had been sold out, and for the 24th time, all blackout restrictions had been lifted.^[8] The streak was ended by the Jacksonville at Buffalo game in Week 12.^[9]

This was the first season that NBC held the rights to televise Sunday Night Football, becoming the beneficiaries by negotiating the new flexible-scheduling system (it also marked the network's return to carrying NFL games since the end of the 1997 season).^[10] ESPN became the new home of Monday Night Football.^[10] Disney-owned corporate sibling ABC had lost millions of dollars on televising MNF during the late 1990s and 2000s despite generating high ratings, and with the NFL wanting Sunday night to be the new night for its marquee game, ABC preferred to protect its Desperate Housewives franchise rather than move the comedy-drama show to another night.^[11][12] By September 2006, ABC began using the ESPN on ABC brand after ABC Sports was fully integrated into ESPN (ABC would not air NFL games again, whether exclusive or a simulcast from ESPN, until they began simulcasting a Wild Card playoff game in 2016, and began simulcasting select MNF games in 2020).^[13] Meanwhile, CBS and Fox renewed their television contracts to the AFC and the NFC packages, respectively.^[14] ESPN's new deal was for eight seasons through 2013, while the new agreements with NBC, CBS, and Fox were initially for six seasons through 2011.^[10][14]

Initially, NBC was able to hire color commentator John Madden, MNF lead producer Fred Gaudelli, and MNF director Drew Esocoff from ABC. However, play-by-play announcer Al Michaels remained under contract with ABC/ESPN, and plans were originally for him to be teamed with Joe Theismann, who would be coming over from ESPN Sunday Night Football.^[15] In February 2006, the two networks' parent companies, The Walt Disney Company and NBCUniversal, agreed to a multi-asset trade that, among others, allowed Michaels to sign with NBC, while Disney took ownership of the intellectual property of Oswald the Lucky Rabbit (a cartoon character developed by Walt Disney himself in the 1920s) from NBCUniversal.^[16] ESPN then opted to go with Mike Tirico on play-by-play, and Theismann and Tony Kornheiser as analysts.^[17]

For its new pregame show Football Night in America, NBC gained the exclusive rights from ESPN's NFL Primetime to show extensive highlights of Sunday afternoon games prior to Sunday Night Football. ESPN responded by moving its show to Mondays. Bob Costas became the host of Football Night in America, while Cris Collinsworth, Jerome Bettis, and Sterling Sharpe became its studio analysts.

The league-owned NFL Network was given an eight-game package, consisting of five Thursday Night Football games and three Saturday game that began airing from Thanksgiving to the end of the regular season. The NFL Network hired HBO Sports' Bryant Gumbel as play-by-play announcer, NBC's Collinsworth as the color commentator for the Thursday telecasts, and Dick Vermeil replacing Collinsworth for Saturday telecasts.

James Brown moved from Fox to CBS, replacing Greg Gumbel as host of The NFL Today. Gumbel then replaced Dick Enberg as the network's #2 play-by-play announcer, and Enberg was demoted to #3.

Fox announced that Joe Buck would replace Brown as lead host on Fox NFL Sunday. Because Buck was already serving as Fox's lead play-by-play announcer, the pregame show was primarily broadcast from the site where Buck was calling the game, and Curt Menefee hosted the halftime and postgame segments. Menefee substituted for Buck as the full-time host when Buck was calling the Major League Baseball playoffs.

Beginning this season and continuing until 2012; CBS would not use sideline reporters for regular season coverage.

• Football Outsiders 2006 DVOA Rankings