The following lists events that happened during 2008 in the Islamic Republic of Iran.

• Supreme Leader: Ali Khamenei
• President: Mahmoud Ahmadinejad
• Vice President: Parviz Davoodi
• Chief Justice: Mahmoud Hashemi Shahroudi

• January 9 – Mehran Ghassemi, 30, Iranian journalist, heart failure.^[6]
• January 13 – Jafar Shahidi, 89, Iranian linguist and historian.^{[citation needed]}
• January 20 – Ghorban Soleimani, 87, Iranian vocalist and dotar player.^[7]
• February 2 – Ahmad Bourghani, 48, Iranian politician, heart failure.^[8]
• February 6 – Nikol Faridani, 72, Iranian aerial photographer, prostate cancer.^[9]
• March 5 – Nader Khalili, 72, Iranian architect, heart failure.^[10]
• March 21 – Shusha Guppy, 72, Iranian writer and singer.^[11]
• March 23 – Maryam Farman Farmaian, 94, Iranian feminist activist.^[12]
• April 12 – Abbas Katouzian, 86, Iranian painter.^{[citation needed]}
• April 15 – Parvin Dowlatabadi, 84, Iranian children's author and poet, heart attack.^[13]
• April 29 – Hassan Dehqani-Tafti, 87, Iranian Anglican Bishop, first ethnic Iranian Christian bishop since the 7th century.^[14]
• July 18 – Khosrow Shakibai, 64, Iranian actor, liver cancer.^{[citation needed]}
• October 9 – Ardeshir Mohassess, 70, Iranian illustrator and cartoonist, heart attack.^[15]
• October 10 – Javad Nurbakhsh, 81, Iranian spiritual leader.
• October 25 – Tahereh Saffarzadeh, 72, Iranian poet and academic, cancer.^[16]