23S_rRNA_(guanine1835-N2)-methyltransferase
23S rRNA (guanine1835-N2)-methyltransferase
Class of enzymes
23S rRNA (guanine1835-N2)-methyltransferase (EC 2.1.1.174, ygjO (gene), rlmG (gene), ribosomal RNA large subunit methyltransferase G) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + guanine1835 in 23S rRNA S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate.