23S_rRNA_(pseudouridine1915-N3)-methyltransferase

23S rRNA (pseudouridine1915-N3)-methyltransferase

23S rRNA (pseudouridine1915-N3)-methyltransferase

Class of enzymes

23S rRNA (pseudouridine1915-N3)-methyltransferase (EC 2.1.1.177, YbeA, RlmH, pseudouridine methyltransferase, m3Psi methyltransferase, Psi1915-specific methyltransferase, rRNA large subunit methyltransferase H) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (pseudouridine1915-N3)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + pseudouridine1915 in 23S rRNA S-adenosyl-L-homocysteine + N3-methylpseudouridine1915 in 23S rRNA
Quick Facts 1915-N3)-methyltransferase, Identifiers ...

YbeA does not methylate uridine at position 1915.

References

  1. [1]
    Ero R, Peil L, Liiv A, Remme J (October 2008). "Identification of pseudouridine methyltransferase in Escherichia coli". RNA. 14 (10): 2223–33. doi:10.1261/rna.1186608. PMC 2553739. PMID 18755836.
  2. [2]
    Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S (October 2008). "YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA". RNA. 14 (10): 2234–44. doi:10.1261/rna.1198108. PMC 2553730. PMID 18755835.
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