6,7-dihydropteridine_reductase
6,7-dihydropteridine reductase
Class of enzymes
In enzymology, 6,7-dihydropteridine reductase (EC 1.5.1.34, also Dihydrobiopterin reductase) is an enzyme that catalyzes the chemical reaction
- 5,6,7,8-tetrahydropteridine + NAD(P)+ 6,7-dihydropteridine + NAD(P)H + H+
The four substrates for this enzyme are a 6,7-dihydropteridine (dihydrobiopterin), NADH, NADPH, and H+ and its three products are 5,6,7,8-tetrahydropteridine (tetrahydrobiopterin), NAD+, and NADP+ This enzyme participates in folate biosynthesis. In the human genome, the enzyme is encoded by the QDPR gene.