Adamkiewicz_reaction

Adamkiewicz reaction

Adamkiewicz reaction

Adamkiewicz reaction


The Adamkiewicz reaction is part of a biochemical test used to detect the presence of the amino acid tryptophan in proteins. When concentrated sulfuric acid is combined with a solution of protein and glyoxylic acid, a red/purple colour is produced. It was named after its discoverer, Albert Wojciech Adamkiewicz.[1][2] Pure sulfuric acid and a minimal amount of pure formaldehyde, along with an oxidizing agent introduced into the sulfuric acid, allow the reaction to proceed. [3]


References

  1. Fearon, Robert William (October 1920). "A Study of some Biochemical Tests. No. 2: The Adamkiewicz Protein Reaction. The Mechanism of the Hopkins-Cole Test for Tryptophan. A New Colour Test for Glyoxylic Acid". Biochem. J. 14 (5): 548–564. doi:10.1042/bj0140548. PMC 1258917. PMID 16742909.



Share this article:

This article uses material from the Wikipedia article Adamkiewicz_reaction, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.