Alkylphosphocholine
Alkylphosphocholine
Class of chemical compounds
Alkylphosphocholines are phospholipid-like molecules that have been synthesised, which have remarkable biological and therapeutic activities.[1][2] They are phosphocholine esters of aliphatic long chain alcohols differing in chain length, unsaturation and position of the cis-double bond.[3]
The utilization of alkylphosphocholine analogues has been found be to useful for the treatment of specific types of cancer, such as gliomas and brain metastases.[4] These analogues function through inhibiting signal transduction pathways of mitosis and triggering apoptosis of cancer cells.[5] Alkylphosphocholine analogues are seen to be more of an efficient treatment for cancer than other drugs as they avoid causing DNA damage and myelotoxicity.[5]