Alpha Pi Omega Sorority, Inc. (ΑΠΩ) is the oldest historically Indigenous national sorority in the United States.^[1][2] It is the largest Indigenous Greek letter organization,^[3] with 24 chartered chapters across nine states and the District of Columbia.^[4]

Alpha Pi Omega Sorority was founded on Sept. 1, 1994, at the University of North Carolina-Chapel Hill by four Native women.^[1][5] The founders, now known to as the Four Winds, are Shannon Brayboy (Lumbee), Jamie Goins (Lumbee), Amy Locklear (Lumbee and Coharie), and Christie Strickland (Lumbee).^[3][5] Before forming the group, they sought and received the approval of elder women from the various tribes of North Carolina.^[5]

The sorority's founding principles are traditionalism, spirituality, education, and contemporary issues.^[1] Its first pledge class was called the Fifteen Warrior Women.^[5] The sorority was incorporated with the State of North Carolina in 1995 and expanded to additional campuses.^[6]

With more than 130 tribes represented by its members, the sorority has more than 900 sisters nationwide. Nationally, the sorority is governed by a thirteen-member board known as the Grand Keepers of the Circle. Grand Keepers are elected to two-year terms and meet bi-monthly.

Alpha Pi Omega preserves Native American traditions by celebrating and practicing cultural and spiritual heritage, such as hosting stickball games.^[6][8] At the same time, it supports a network for college students and professionals in modern society.^[5] The sorority's annual national convention is called the Grand Gathering.^[9]

Its permanent national philanthropy is the National Indian Education Association, as of 2010.^[6][7] Individual chapters also participate in local fundraising events such as Walk a Mile in Her Shoes or Remember the 10 Run.^[9][8] The Washington State University chapter held sexual assault awareness classes and LGBTQ+ ally training, while the Oregon State University chapter held a fundraiser for the Humane Society.^[10][8]

Interested women may join at the undergraduate or post-undergraduate level. Collegiate women must have completed at least one full-time academic term, have a 2.8 GPA or higher, and have no previous affiliation with any social sorority.^[6] Women interested in joining a professional chapter must have completed a bachelor's degree or higher and have no previous affiliation with any social sorority.

APO starts potential chapters as expansion chapters or honey pots.^[10] After a year, the expansion chapter becomes a provisional chapter.^[10] Chapters are chartered at the sorority's annual Grand Gathering.^[10] Graduate chapters are for women who have received their undergraduate degrees.^[7]

Active chapters are indicated in bold. Inactive chapters are shown in italic.

• Cultural interest fraternities and sororities
• List of social fraternities and sororities
• Phi Sigma Nu fraternity