Antiglucocorticoid

Antiglucocorticoid

Antiglucocorticoid

Class of pharmaceutical drugs

An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.

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Antiglucocorticoids could be effective antidepressants for a subset of specific mood disorders, but their use is limited by side effects.[1]

See also

References

  1. [1]
    Gallagher P, Malik N, Newham J, Young AH, Ferrier IN, Mackin P (2008). MacKin P (ed.). "Antiglucocorticoid treatments for mood disorders". Cochrane Database of Systematic Reviews (1): CD005168. doi:10.1002/14651858.CD005168.pub2. PMID 18254070. (Retracted, see doi:10.1002/14651858.cd005168.pub3. If this is an intentional citation to a retracted paper, please replace {{Retracted}} with {{Retracted|intentional=yes}}.)


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