The Arkansas–Fort Smith Lions (also UAFS Lions and UA Fort Smith Lions) are the athletic teams that represent the University of Arkansas–Fort Smith, located in Fort Smith, Arkansas, in NCAA Division II intercollegiate sports. The Lions compete as members of the Lone Star Conference for all 10 varsity sports.

In the fall of 2009, UAFS formally entered provisional NCAA Division II status. The "provisional" status was scheduled to be removed in 2010. However, on July 9, 2010, the university's membership application was rejected by the NCAA Division II Membership Committee, which led to the university filing an appeal.^[2] On July 8, 2011, the university was granted full NCAA Division II membership.^[3] Previously, the university competed in the National Junior College Athletic Association (NJCAA), specifically at the Bi-State Conference of Region II.

On June 27, 2023, UAFS announced that it would be moving its athletic programs from the Lone Star Conference to the Mid-America Intercollegiate Athletics Association. University officials cited reduced travel times and better potential for rivalries as reasons for the move.^[4]