Bedfordshire and Milton Keynes was a constituency of the European Parliament located in the United Kingdom, electing one Member of the European Parliament by the first-past-the-post electoral system. Created in 1994 from parts of Cambridge and Bedfordshire North and Suffolk, it was abolished in 1999 on the adoption of proportional representation for European elections in the United Kingdom. It was mostly succeeded by the East of England region, with the remaining part succeeded by the South East England region.

It consisted of the parliamentary constituencies of Luton North, Luton South, Mid Bedfordshire, Milton Keynes South West, North Bedfordshire, North East Milton Keynes and South West Bedfordshire.^[1]

Mid Bedfordshire and North Bedfordshire had previously been part of the Cambridge and Bedfordshire North constituency, while Luton North, Luton South, Milton Keynes South West, North East Milton Keynes and South West Bedfordshire had been part of the Bedfordshire South constituency.

Most of the area became part of the East of England constituency in 1999; the Milton Keynes constituencies became part of the South East England constituency.