Callicarpenal

Callicarpenal

Callicarpenal

Chemical compound

Callicarpenal is a terpenoid that has been isolated from plants of the genus Callicarpa (beautyberry).[1] It acts as an insect repellent against mosquitoes (Aedes aegypti and Anopheles stephensi) and fire ants.[1][2] It also has activity against ticks (Ixodes scapularis and Amblyomma americanum).[3]

Quick Facts Names, Identifiers ...

In comparison to the most commonly used insect repellent, DEET, callicarpenal is only about 21% less effective at preventing mosquito bites.[4]

Callicarpenal was discovered by scientists at the United States Department of Agriculture's Agricultural Research Service who were inspired by reports that Callicarpa americana (American beautyberry) was used as a folk remedy to prevent mosquito bites.[5]

References

  1. [1]
    Cantrell, C. L.; Klun, J. A.; Bryson, C. T.; Kobaisy, M.; Duke, S. O. (2005). "Isolation and Identification of Mosquito Bite Deterrent Terpenoids from Leaves of American (Callicarpa americana) and Japanese (Callicarpa japonica) Beautyberry". Journal of Agricultural and Food Chemistry. 53 (15): 5948–53. doi:10.1021/jf0509308. PMID 16028979.
  2. [2]
    Chen, J; Cantrell, CL; Duke, SO; Allen, ML (2008). "Repellency of callicarpenal and intermedeol against workers of imported fire ants (Hymenoptera: Formicidae)". Journal of Economic Entomology. 101 (2): 265–71. doi:10.1603/0022-0493(2008)101[265:ROCAIA]2.0.CO;2. PMID 18459387.
  3. [3]
    Carroll, JF; Cantrell, CL; Klun, JA; Kramer, M (2007). "Repellency of two terpenoid compounds isolated from Callicarpa americana (Lamiaceae) against Ixodes scapularis and Amblyomma americanum ticks". Experimental & Applied Acarology. 41 (3): 215–24. doi:10.1007/s10493-007-9057-2. PMID 17380408. S2CID 13138655.
  4. [4]
    Ling, Taotao; Xu, Jing; Smith, Ryan; Ali, Abbas; Cantrell, Charles L.; Theodorakis, Emmanuel A. (2011). "Synthesis of (−)-callicarpenal, a potent arthropod repellent". Tetrahedron. 67 (17): 3023–3029. doi:10.1016/j.tet.2011.02.078. PMC 3105892. PMID 21643472.
  5. [5]
    Luis Pons (February 2006). "Folk Remedy Yields Mosquito-Thwarting Compound". Agricultural Research Magazine. 54 (2).
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