The Cayman Islands has competed at every edition of the Pan American Games since the ninth edition of the multi-sport event in 1987. The Cayman Islands did not compete at the first and only Pan American Winter Games in 1990.

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Summer

More information Year, Ref. ...

Year	Ref.	Edition	Host city	Rank	Gold	Silver	Bronze	Total
1951	[1]	I	Buenos Aires	Did not participate
1955	[2]	II	Mexico City	Did not participate
1959	[3]	III	Chicago	Did not participate
1963	[4]	IV	São Paulo	Did not participate
1967	[5]	V	Winnipeg	Did not participate
1971	[6]	VI	Cali	Did not participate
1975	[7]	VII	Mexico City	Did not participate
1979	[8]	VIII	San Juan	—	0	0	0	0
1983	[9]	IX	Caracas	—	0	0	0	0
1987	[10]	X	Indianapolis	—	0	0	0	0
1991	[11]	XI	Havana	—	0	0	0	0
1995	[12]	XII	Mar del Plata	—	0	0	0	0
1999	[13]	XIII	Winnipeg	23rd	0	1	0	1
2003	[14]	XIV	Santo Domingo	23rd	0	1	0	1
2007	[15]	XV	Rio de Janeiro	23rd	0	1	0	1
2011	[16]	XVI	Guadalajara	15th	1	1	1	3
2015		XVII	Toronto	—	0	0	0	0
2019		XVIII	Lima	—	0	0	0	0
Total				27th	1	4	1	6

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Winter

More information Year, Ref. ...

Year	Ref.	Edition	Host city	Rank	Gold	Silver	Bronze	Total
1990	[17]	I	Las Leñas	Did not participate
Total				—	0	0	0	0

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