Clocortolone_pivalate

Clocortolone pivalate

Clocortolone pivalate

Chemical compound

Clocortolone pivalate (brand names Cilder, Cloderm, Purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in the United States and Austria.[1][2][3] It is the C21 pivalate (trimethylacetate) ester of clocortolone,[1][2] and acts as a prodrug of clocortolone in the body.[4][5]

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References

  1. [1]
    Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 293–. ISBN 978-1-4757-2085-3.
  2. [2]
    Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 253–. ISBN 978-3-88763-075-1.
  3. [3]
    Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 79–. ISBN 978-94-011-4439-1.
  4. [4]
    US 5073641, Bundgaard H, Nielsen NM, "Prodrug derivatives of carboxylic acid drugs", issued 17 December 1991
  5. [5]
    Stella V, Borchardt R, Hageman M, Oliyai R, Maag H, Tilley J (12 March 2007). Prodrugs: Challenges and Rewards. Springer Science & Business Media. pp. 220–. ISBN 978-0-387-49782-2.



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