Clofibric_acid

Clofibric acid

Clofibric acid

Chemical compound

Clofibric acid is a biologically active metabolite of the lipid-lowering drugs clofibrate, etofibrate and theofibrate[1][2] with the molecular formula C10H11ClO3. It has been found in the environment following use of these drugs, for example in Swiss lakes and the North Sea.[2][3]

Quick Facts Names, Identifiers ...

Some derivatives of clofibric acid are in a drug class called fibrates.

See also

References

  1. [1]
    Salgado, R.; Oehmen, A.; Carvalho, G.; Noronha, J.P.; Reis, M.A.M. (2012). "Biodegradation of clofibric acid and identification of its metabolites". Journal of Hazardous Materials. 241–242: 182–189. doi:10.1016/j.jhazmat.2012.09.029. PMID 23062606.
  2. [2]
    Packer, Jennifer L; Werner, Jeffrey J; Latch, Douglas E; McNeill, Kristopher; Arnold, William A (2003). "Photochemical fate of pharmaceuticals in the environment: Naproxen, diclofenac, clofibric acid, and ibuprofen". Aquatic Sciences. 65 (4): 342–351. doi:10.1007/s00027-003-0671-8. S2CID 24063392.
  3. [3]
    Buser, Hans-Rudolf; Müller, Markus D; Theobald, Norbert (1998). "Occurrence of the Pharmaceutical Drug Clofibric Acid and the Herbicide Mecoprop in Various Swiss Lakes and in the North Sea". Environmental Science & Technology. 32 (1): 188–192. Bibcode:1998EnST...32..188B. doi:10.1021/es9705811.


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