DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose_N,N-dimethyltransferase

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase

dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase

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DTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase (EC 2.1.1.236, RavNMT) is an enzyme with systematic name S-adenosyl-L-methionine:dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N,N-dimethyltransferase.[1] This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 2 S-adenosyl-L-homocysteine + dTDP-3-dimethylamino-3,6-dideoxy-alpha-D-galactopyranose
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The enzyme is involved in the synthesis of dTDP-D-ravidosamine.

References

  1. [1]
    Kharel MK, Lian H, Rohr J (March 2011). "Characterization of the TDP-D-ravidosamine biosynthetic pathway: one-pot enzymatic synthesis of TDP-D-ravidosamine from thymidine-5-phosphate and glucose-1-phosphate". Organic & Biomolecular Chemistry. 9 (6): 1799–808. doi:10.1039/c0ob00854k. PMC 4482361. PMID 21264378.
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