DTDP-4-amino-4,6-dideoxy-D-glucose_acyltransferase

dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase

dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase

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DTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase (EC 2.3.1.209, VIOB) is an enzyme with systematic name acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-glucose N-acetyltransferase.[1] This enzyme catalyses the following chemical reaction

acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose
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4-acetamido-4,6-dideoxy-alpha-D-glucose is part of the O antigens of Shigella dysenteriae type 7 and Escherichia coli O7.

References

  1. [1]
    Wang Y, Xu Y, Perepelov AV, Qi Y, Knirel YA, Wang L, Feng L (December 2007). "Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7". Journal of Bacteriology. 189 (23): 8626–35. doi:10.1128/jb.00777-07. PMC 2168959. PMID 17905981.
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