Eleni Tositsa (1796 – 1 April 1866; Greek: Ελένη Τοσίτσα) was a major benefactor to cultural and educational establishments in Greece, including the National Archaeological Museum and the National Technical University of Athens.

Eleni Tositsa was born in Metsovo, Epirus, in 1796.^[1][2] She married Michael Tositsas in 1818 and moved with him first to Alexandria in 1820 and then to Athens in 1854.^[3] During the Greek revolution, she organised the buying and freeing of enslaved Greeks from Egyptian slave markets.^[4][2] After her husband's death in 1855, she inherited most of his property, which he instructed in his will should be used to benefit the Greek state.^[2] Tositsa donated large sums of this money to various schools, including funding a new building for the Educational Society's girls' school (known as the Tositseion),^[3] and founding a girls' school in her hometown of Metsovo, and to Queen Amalia's Orphanage.^{[4][2][1][5][6]}

On 14 May 1860, she donated a plot of land to the Hellenic State to provide a site for the National Metsovio Technical University, also known as the National Technical University of Athens or the Polytechnic;^[4] the university transferred to this site on Patission Street in 1871.^[7] The name 'Metsovio' refers to the town of Metsovo in Epirus, the hometown of Eleni Tositsa and Michael Tositsas as well as two other benefactors, Nikolaos Stournaris and Georgios Averof.^[7]

The National Archaeological Museum, which was originally located in Aegina, was transferred to Athens when this city became the capital in 1834; construction of a purpose-built building began in 1866 after Tositsa donated the plot of land on which the museum is now located, and the building opened to the public in 1889.^[8][9] The street which runs between the museum and the National Technical University is now named Tositsa Street (Οδός Τοσίτσα).^[10]

She died on April 1, 1866, in Athens.^[3]